Why the study?
Does perioperative landiolol administration reduce postoperative atrial fibrillation in patients undergoing cardiac surgery?
Population
6 RCTs pooling 560 Japanese patients undergoing cardiac surgery. Key exclusions: history of arrhythmia…
Comparison
Perioperative landiolol continuous intravenous… vs Control group receiving saline, no treatment, or…
Design
Meta-analysis, Included studies were randomized controlled trials., Only two…
Follow-up
At least 3 days
Authors
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Supports perioperative landiolol to prevent POAF after cardiac surgery; confirms benefit across aggregated trials.
Does perioperative landiolol administration reduce postoperative atrial fibrillation in patients undergoing cardiac surgery?
Perioperative intravenous administration of the ultra-short-acting beta-blocker landiolol significantly reduces the incidence of postoperative atrial fibrillation after cardiac surgery and is well tolerated.
Sakamoto et al. (2014) studied this question.
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