Why the study?
How does perfusion pressure contribute to vascular resistance response in the arm versus leg during head-up tilt?
Population
8 subjects (5 subjects for muscle sympathetic nerve activity measurements)
Comparison
Head-up tilt testing to 40 degrees vs Baseline/supine state and comparison between arm…
Design
Other
Authors
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Greater leg vasoconstriction during tilt may affect orthostatic hemodynamic assessments; leaves open perfusion pressure's role in regional resistance.
How does perfusion pressure contribute to vascular resistance response in the arm versus leg during head-up tilt?
The greater vascular resistance response in the leg during head-up tilt suggests an interaction between sympathetic nerve activity and the myogenic response.
Imadojemu et al. (2001) studied this question.
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