January 18, 2013Heart

Moderate overweight is beneficial and severe obesity detrimental for patients with documented atherosclerotic heart disease

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Why the study?

Does body mass index category influence survival in patients with documented atherosclerotic heart disease?

Structured PICO

Does body mass index category influence survival in patients with documented atherosclerotic heart disease?

Population

37,573 patients with coronary atherosclerosis confirmed by coronary angiography from the Western Denmark Heart Registry, mean age 66.3 years, 70.7% men.

Intervention

Different Body Mass Index (BMI) categories based on WHO classification (e.g., preobese, low BMI, very high BMI)

Comparator

Reference group with normal weight (23 ≤ BMI < 25 kg/m²)

Outcome

Mortality (death) during 11 years of follow-uphard clinical

In patients with established coronary atherosclerosis, being overweight is associated with improved survival compared to normal weight, whereas underweight and severe obesity are associated with increased mortality, supporting an 'overweight paradox'.

Discussion

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Implication

May support overweight paradox in atherosclerotic heart disease; hypothesis-generating and should not yet change practice.

Cite This Study

Azimi et al. (2013) studied this question.

synapsesocial.com/papers/6a7e75c11fdb7ee677c7718c https://doi.org/10.1136/heartjnl-2012-303066

Topics

Coronary artery disease

View Full Paper

Ask AI

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Moderate overweight is beneficial and severe obesity detrimental for patients with documented atherosclerotic heart disease

Structured PICO

Discussion

Implication

Cite This Study

Topics

Moderate overweight is beneficial and severe obesity detrimental for patients with documented atherosclerotic heart disease

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider