Answers are grounded in this paper and cite their sources.
Dysregulation of the cell cycle underlies many human genetic diseases and cancers, yet numerous organisms, including microbes, also manipulate the cell cycle to generate both morphologic and genetic diversity as a natural mechanism to enhance their chances for survival. The eukaryotic pathogen Cryptococcus neoformans generates morphologically distinct polyploid titan cells critical for host adaptation and subsequent disease.
No takes yet. Share an insight, caveat, or question.
Altamirano et al. (2021) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: