Why the study?
Do patients with fibromyalgia have altered 24-hour cardiovascular autonomic modulation and circadian variations compared to healthy controls?
Population
30 patients with fibromyalgia and 30 age- and sex-matched controls (n=60)
Comparison
Fibromyalgia (observational) vs Age- and sex-matched controls
Design
Case-control
Follow-up
24 hours
Authors
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Hypothesis-generating for dysautonomia in fibromyalgia; prospective studies needed to clarify cardiovascular risk.
Do patients with fibromyalgia have altered 24-hour cardiovascular autonomic modulation and circadian variations compared to healthy controls?
Fibromyalgia patients exhibit diminished 24-hour heart rate variability and abnormal circadian sympathovagal balance, suggesting dysautonomia with exaggerated nocturnal sympathetic modulation.
Mart�nez-Lav�n et al. (1998) studied this question.
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