Why the study?
Although reports of SARS-CoV-2 myocarditis exist, the majority lack histological confirmation of cardiac injury.
This case report provides histological and genetic evidence of direct cardiac involvement compatible with fulminant myocarditis in a patient with SARS-CoV-2 infection.
Case report of SARS-CoV-2 myocarditis adds to literature; leaves open questions on incidence, causality, and management.
There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range of clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, acute myocardial ischemia and pulmonary thromboembolism to long-term cardiovascular sequelae. In particular, acute myocarditis represents an uncommon but frightening complication of SARS-CoV-2 infection. Even if many reports of SARS CoV-2 myocarditis are present in the literature, the majority of them lacks histological confirmation of cardiac injury. Here, we report a case of a young lady, who died suddenly a few days after testing positive for SARS-CoV-2, whose microscopic and genetics features suggested a direct cardiac involvement compatible with fulminant myocarditis.
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Pierri et al. (2023) studied this question.
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