Why the study?
Despite evolving guideline-directed therapies with mortality benefits, diuretics remain essential for managing clinical congestion across all forms of heart failure, requiring clinical familiarity with dosing and monitoring.
Diuretics remain a key component in managing clinical congestion in all forms of heart failure, alongside guideline-directed medical therapies.
Reserve diuretics for congestion once euvolemic to enable GDMT; reinforces their adjunctive role and leaves optimal weaning open.
Heart failure is an increasingly prevalent condition resulting in recurrent hospitalisations and significant mortality and morbidity. The management of heart failure has evolved, and multiple drugs have an established mortality benefit in heart failure with reduced ejection fraction. Although the focus should be on ensuring that patients are treated with the maximum tolerated doses of these guideline-directed therapies, diuretics continue to play a key role in the management of clinical congestion in all forms of heart failure. Clinicians play a key role in heart failure management. Familiarity with the role of diuretics and their dosing and monitoring is critical.
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McVeigh et al. (2022) studied this question.
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