Key result
Diuretic management for HF congestion remains complicated by frequent resistance and limited trial data.
Why the study?
Diuretics are widely used for congestion in heart failure, but management remains challenging due to a lack of large controlled studies and the development of resistance or tolerance.
A comprehensive review of diuretic therapies in heart failure, emphasizing the mechanisms of action, clinical applications, and strategies to overcome diuretic resistance.
Clinicians face ongoing diuretic resistance challenges in HF congestion; leaves open optimal strategies pending dedicated RCTs.
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Seguro et al. (2022) conducted a review in Heart Failure. Diuretics was evaluated. Diuretics are the primary treatment for congestion in heart failure, but their management is challenged by a lack of large controlled trials and the frequent development of diuretic resistance.
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