Why the study?
Pulmonary artery pseudoaneurysm is a rare presentation of metastatic neoplasm with high rupture mortality, and cases related to neoplasm are rarely reported.
Highlights the rare presentation of pulmonary artery pseudoaneurysm secondary to metastatic uterine leiomyosarcoma, emphasizing early diagnosis via CT angiogram and endovascular treatment.
May prompt PAP evaluation amid dyspnea in metastatic uterine leiomyosarcoma; leaves open intervention feasibility in advanced disease.
Pulmonary artery pseudoaneurysm (PAP) is a rare presentation of metastatic neoplasm. The mechanism of formation of PAP is thought to be due to tumor embolus penetration of the vessel wall and the formation of saccular dilation that is more prone to rupture than systemic arterial aneurysms. The leading cause of PAP is infection, and PAP related to neoplasm has rarely been reported. Early diagnosis and treatment are crucial as mortality associated with PAP rupture has been reported from 50-100%. CT pulmonary angiogram is the best approach for diagnosing PAP. Once the diagnosis is confirmed treatment depends on the etiology and clinical condition of the patient, but the favored first-line treatment is endovascular therapy.
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Noff et al. (2024) studied this question.
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