Frailty, a critical intermediate status of the ageing process, can be defined as a unidimensional entity, mainly based on the physical or biological dimension, or as a non-specific multidimensional status based on a deficit accumulation model and different and interconnected domains.1 Due to its multidimensional and multisystem nature, frailty could include physical, sensorial, social, cognitive, psychological, and nutritional domains or phenotypes that need to be taken into account in its definition, management, and prevention.
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Lozupone et al. (2020) studied this question.
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