Toxicity of mefloquine is similar to that of other chemoprophylaxis

EDITOR,--The revised guidelines on chemoprophylaxis against malaria perpetuate the notion that mefloquine is relatively innocuous when used for this purpose.1 This view has been challenged by some authorities,2 who argue that the side effects of mefloquine have been greatly underreported. As White recognised in an editorial on mefloquine, this tendency to understate the toxicity of the durg has followed from the poor scientific quality of almost all of the early studies on use of mefloquine.3 View this table: Incidence of adverse events to malaria chemoprophylaxis of …