Population
Human embryo fibroblasts
Design
Preclinical
Authors
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Provides in vitro model of interferon-responsive persistent HAV; leaves open clinical translation and further validation needed.
HAV establishes a persistent infection in human fibroblasts in vitro that can be eliminated by exogenous interferon, providing a model to study immunological injury in HAV infection.
Vallbracht et al. (1984) studied this question.
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