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October 16, 2025Journal of the American Geriatrics Society

Overall, 20.8% of patients had an antithrombotic prescription on hospice admission, which was significantly more likely in patients with better prognosis (e.g., PPS 60%-100% aOR 15.67, 95% CI 12.41-19.79) and those in non-inpatient settings.

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Why the study?

Little is known regarding antithrombotic prescribing in U.S. hospice patients.

What is the prevalence and what are the predictors of receiving an antithrombotic prescription on hospice admission in adult hospice patients?

Population

54,643 adult decedents of a large for-profit hospice chain who died between 2017 and 2019

Comparison

Receiving vs not receiving an antithrombotic prescription on hospice admission

Design

Cross-sectional study

Authors

ESEmily K. ShortJTJennifer TjiaMAMatthew Alcusky

Discussion

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Member takes

Overview

May prompt careful review rather than automatic deprescribing; leaves open the net benefit of antithrombotics in hospice.

Structured PICO

What is the prevalence and what are the predictors of receiving an antithrombotic prescription on hospice admission in adult hospice patients?

P
Population
54,643 adult (age ≥ 18 years) decedents of a large, for-profit U.S. hospice chain who died between January 1, 2017, and December 31, 2019, mean age 79.7, 44.6% male.
I
Intervention
Antithrombotic (anticoagulant or antiplatelet) therapy prescription on hospice admission
O
Outcome
Having a prescription for antithrombotic (anticoagulant or antiplatelet) therapy on hospice admission

Antithrombotic therapy remains highly prevalent upon hospice admission, particularly among patients with better functional status and those in non-inpatient care settings.

Cite This Study

Short et al. (2025) studied this question.

synapsesocial.com/papers/6a7eb539358787acda4f7c35https://doi.org/10.1111/jgs.70170
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence and Factors Associated with Receiving a Prescription for a Direct Oral Anticoagulant Among Patients with Atrial Fibrillation on Hospice Admission2026
  2. 2Predictors of antithrombotic deprescribing in older patients with advanced cancer and limited life expectancy in hospice care: a retrospective cohort study2026
  3. 3Discontinuation of oral anticoagulant use among nursing home residents with atrial fibrillation before hospice enrollment2023 · 6 citations
  4. 4Antithrombotic therapy at the end-of-life—continue or stop?2026 · 1 citations
  5. 5Antithrombotic Therapy Practices in Older Adults Residing in the Long-Term Care Setting2015 · 3 citations