Simplifying the ion source for mass spectrometry

Figure S1: Mass spectra of bradykinin (MW 1059.6) using the commercial intermediate pressure vacuum MALDI source for MAIV sample introduction. (a) 2.5 pmol of bradykinin in 3-NBN matrix was deposited using the dried droplet method on a commercial MALDI sample plate. After the first MAIV acquisition was completed, only matrix dissolved in 1:1 ACN:water was added to the sample plate. The process of adding just matrix solution to the same spot followed by mass spectral acquisitions until ionization was complete was repeated (b) 10 times and (c) 20 times. Figure S2: Mass spectra of bradykinin (MW 1059.6) applying (a) 250 fmol and (b) 25 fmol in the 3-NBN matrix solution to the probe. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.