March 1, 2003Asian Cardiovascular and Thoracic Annals
Impact of Preoperative Renal Dysfunction on Cardiac Surgery Results
Why the study?
Does preoperative renal dysfunction predict morbidity and mortality in patients undergoing cardiac surgery?
Population
2,214 patients undergoing cardiac surgery, of whom 507 had preoperative renal dysfunction (creatinine…
Comparison
Preoperative renal dysfunction (exposure) vs Normal preoperative renal function
Design
Cohort
Follow-up
18 months
Authors
Discussion
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Member takes
Implication
May warrant enhanced preoperative renal assessment in cardiac surgery; leaves open whether renoprotective strategies improve survival.
Structured PICO
Does preoperative renal dysfunction predict morbidity and mortality in patients undergoing cardiac surgery?
P
Population
2,214 patients undergoing cardiac surgery, of whom 507 had preoperative renal dysfunction (creatinine clearance < 0.9 mL x s(-1) x m(-2))
I
Intervention
Preoperative renal dysfunction (exposure)
C
Comparator
Normal preoperative renal function
O
Outcome
Morbidity and mortalityhard clinical
Preoperative renal dysfunction, specifically a creatinine clearance < 0.84 mL x s(-1) x m(-2), is an independent predictor of exponentially increased morbidity and mortality following cardiac surgery.
Cite This Study
Abramov et al. (2003) studied this question.