Why the study?
Papillary muscle rupture retains a high fatality rate, but early diagnosis is challenging due to nonspecific symptoms.
Elevated inflammatory markers such as C-reactive protein and neutrophil-to-lymphocyte ratio after myocardial infarction may serve as early warning signs for mechanical complications like papillary muscle rupture.
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May heighten PMR suspicion with dual OM-diagonal lesions and rising CRP/NLR; leaves open prospective validation before practice change.
Koyama et al. (2023) studied this question.
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