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July 1, 1991Journal of Veterinary Internal Medicine

Plasma Taurine Concentrations and M-mode Echocardiographic Measures in Healthy Cats and in Cats with Dilated Cardiomyopathy

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Why the study?

Does taurine supplementation improve clinical outcomes in cats with dilated cardiomyopathy and low plasma taurine concentrations?

Population

156 cats, comprising 79 healthy cats and 77 cats with dilated cardiomyopathy (DCM)

Design

Preclinical

Follow-up

up to 4 to 8 weeks

Authors

DSD. David SissonUniversity of Illinois Urbana-ChampaignDKD. H. KnightUniversity of Cape TownCHCecelia HelinskiUniversity of Pennsylvania

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Implication

Hypothesis-generating for taurine supplementation in feline DCM; prospective trials needed before clinical adoption.

Structured PICO

Does taurine supplementation improve clinical outcomes in cats with dilated cardiomyopathy and low plasma taurine concentrations?

P
Population
156 cats, comprising 79 healthy cats and 77 cats with dilated cardiomyopathy (DCM)
I
Intervention
Taurine supplementation
O
Outcome
Relationship between plasma taurine concentrations and M-mode echocardiographic measurements, and clinical response/survival after taurine supplementation

Low plasma taurine concentrations are highly prevalent in cats with dilated cardiomyopathy, and taurine supplementation can lead to clinical improvement in a subset of these animals.

Cite This Study

Sisson et al. (1991) studied this question.

synapsesocial.com/papers/6a7ec69cdd58934418cd9d4chttps://doi.org/10.1111/j.1939-1676.1991.tb00954.x

Topics

Echocardiography
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.1978 · 7,474 citations
  2. 2STUDIES OF UNBOUND AMINO ACID DISTRIBUTIONS IN PLASMA, ERYTHROCYTES, LEUKOCYTES AND URINE OF NORMAL HUMAN SUBJECTS1960 · 102 citations
  3. 3Retinal Degeneration Associated with Taurine Deficiency in the Cat1975 · 596 citations