Why the study?
To examine whether baseline depression is associated with MI within a 2-year period among middle-age and older adults in China and whether this association varies by sociodemographic characteristics.
Does baseline depression increase the risk of myocardial infarction within a 2-year period in middle-age and older adults?
Does baseline depression increase the risk of myocardial infarction within a 2-year period in middle-age and older adults?
Clinically significant depression is associated with a 46% increased odds of myocardial infarction over a 2-year period in Chinese adults aged 45 and older.
We examined whether baseline depression is associated with myocardial infarction (MI) within a 2-year period among middle-age and older adults in China and whether the association varies by sociodemographic characteristics. Two-year longitudinal data from a nationally representative sample of people aged 45+ years in China were analyzed (N = 15 226). MI within the 2-year period was coded dichotomously. Baseline depression, assessed by the 10-item Center for Epidemiological Studies Depression scale, was used as a dichotomous and a continuous variable. After adjusting for medical conditions, lifestyle, and sociodemographic characteristics, the odds of having an MI within the 2-year period were 46% greater for respondents with clinically significant depression at baseline than those without. There was a dose-response relationship between symptom severity and the probability of having an MI. The association did not vary by sociodemographic characteristics. Findings suggested that depression screening and treatment may reduce MI cases in China and beyond.
No takes yet. Share an insight, caveat, or question.
Li et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: