Why the study?
The study was conducted to demonstrate the correlation between coronary collateral circulation and atherogenic plasma index in patients with chronic coronary total occlusion.
Does atherogenic plasma index predict collateral development in patients with chronic coronary total occlusion?
Does atherogenic plasma index predict collateral development in patients with chronic coronary total occlusion?
Low atherogenic plasma index is an independent predictor of good collateral artery formation in patients with chronic coronary total occlusion.
Should not yet change practice in CTO; leaves open whether AIP independently predicts or modifies collateral formation.
To demonstrate the correlation between coronary collateral circulation (CCC) and atherogenic plasma index (AIP), one of the factors associated with the formation of collateral vessels. Methods: Hospital records of patients with chronic total occlusion (100% stenosis) in at least one coronary artery were evaluated. Triglycerides, HDL level, triglyceride/HDL ratio and atherogenic plasma index before coronary angiography were assessed for the 451 patients who met the study criteria. Results: Comparison of the two groups in terms of laboratory findings showed that triglyceride/HDL ratio (5.043.13 vs 3.562.12, p<0.001) and AIP (0.630.25 vs 0.480.25, p<0.001) were higher with statistical significance in the weak collateral group. The ROC analysis revealed an association between weak collateral formation and atherogenic plasma index with 64.7% sensitivity and 66.2% specificity using a cut-off value of 0.58 for AIP. Accordingly, low AIP was found to be an independent predictor of good collateral artery formation.
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Güzel et al. (2021) studied this question.
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