What question did this study set out to answer?

To evaluate whether a preoperative rhomboid intercostal plane block reduces chronic postoperative pain incidence, acute pain scores, and opioid consumption in women undergoing oncologic breast surgery.

August 14, 2026BMC AnesthesiologyOpen Access

Impact of rhomboid intercostal plane block on chronic pain incidence and acute pain scores after oncologic breast surgery: a randomized controlled trial

View Full Paper

Ask AI

Bookmark

Authors

TKTolga Karaçay BABaşak Altıparmak SPSinan Pektaş

Discussion

Member takes

Overview

Randomized double-blind trial demonstrates reduced chronic pain and opioid use after breast cancer surgery, indicating effective long-term regional analgesia.

Key Points

To evaluate whether a preoperative rhomboid intercostal plane block reduces chronic postoperative pain incidence, acute pain scores, and opioid consumption in women undergoing oncologic breast surgery.
Prospective, single-center, randomized, double-blind controlled trial in 254 adult women undergoing oncologic breast surgery with or without lymph node dissection (NCT06019325; 247 completed).
Patients were randomized to receive either a preoperative ultrasound-guided single-shot rhomboid intercostal plane block with 30 mL of 0.25% bupivacaine or no regional block, with both groups receiving standardized multimodal systemic analgesia.
Primary outcome was chronic pain incidence at 3 months postoperatively; secondary outcomes included chronic pain at 6 months, neuropathic pain (DN4), and 24-hour opioid consumption.
Chronic pain incidence was significantly lower in the block group compared with controls at 3 months (17% vs 31%; p = 0.009) and at 6 months (13% vs 30%; p < 0.001).
Patients receiving the block had lower 24-hour postoperative opioid consumption (p = 0.01) and reduced neuropathic pain at 6 months.

Cite This Study

Karaçay et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec71db70b84ec8b9133d3 https://doi.org/10.1186/s12871-026-04175-2

View Full Paper

Ask AI

Bookmark

August 14, 2026BMC AnesthesiologyOpen Access

Impact of rhomboid intercostal plane block on chronic pain incidence and acute pain scores after oncologic breast surgery: a randomized controlled trial

View Full Paper

Ask AI

Bookmark

Authors

TKTolga Karaçay BABaşak Altıparmak SPSinan Pektaş

Discussion

Member takes

Overview

Randomized double-blind trial demonstrates reduced chronic pain and opioid use after breast cancer surgery, indicating effective long-term regional analgesia.

Key Points

To evaluate whether a preoperative rhomboid intercostal plane block reduces chronic postoperative pain incidence, acute pain scores, and opioid consumption in women undergoing oncologic breast surgery.
Prospective, single-center, randomized, double-blind controlled trial in 254 adult women undergoing oncologic breast surgery with or without lymph node dissection (NCT06019325; 247 completed).
Patients were randomized to receive either a preoperative ultrasound-guided single-shot rhomboid intercostal plane block with 30 mL of 0.25% bupivacaine or no regional block, with both groups receiving standardized multimodal systemic analgesia.
Primary outcome was chronic pain incidence at 3 months postoperatively; secondary outcomes included chronic pain at 6 months, neuropathic pain (DN4), and 24-hour opioid consumption.
Chronic pain incidence was significantly lower in the block group compared with controls at 3 months (17% vs 31%; p = 0.009) and at 6 months (13% vs 30%; p < 0.001).
Patients receiving the block had lower 24-hour postoperative opioid consumption (p = 0.01) and reduced neuropathic pain at 6 months.

Cite This Study

Karaçay et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec71db70b84ec8b9133d3 https://doi.org/10.1186/s12871-026-04175-2

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark