Case report demonstrates Strongyloides reactivation causing larva currens in an older COVID-19 patient treated with dexamethasone, highlighting risks of immunosuppressive therapies.
The approach to diagnosis and treatment of COVID-19 infection has evolved through the years, and the use of immunosuppressive therapy is now increasingly mainstream. Simultaneously, we see a rise in reactivation of latent infections with such use of immunosuppressive therapy. We report a case of Strongyloides reactivation in the form of cutaneous Strongyloidiasis in a 77-year-old Singaporean Chinese woman, following treatment of COVID-19 pneumonia with a short course of dexamethasone. With the ease of availability and widespread use of immunosuppressants in COVID 19 infection, this case serves to remind us to have a high index of suspicion for reactivation of latent infections in the appropriate patient population.
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Tan et al. (2026) studied this question.
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