What question did this study set out to answer?

To evaluate evidence on the implementation, clinical outcomes, and challenges of integrated care for HIV, non-communicable diseases, and mental health conditions among adolescents and young adults in primary healthcare settings across low- and middle-income countries.

August 14, 2026Discover Public HealthOpen Access

Integrated management of HIV, non-communicable diseases and mental health in adolescents and young adults in primary health care settings in LMICs: a systematic review

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Authors

ETEdwin Tsitsi TMTshimangadzo Selina Mudau SMSamuel T. Matula

Discussion

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Overview

Systematic review reveals feasible benefits and systemic barriers for integrated HIV, chronic disease, and mental healthcare in young people, indicating a need for youth-tailored primary care.

Key Points

To evaluate evidence on the implementation, clinical outcomes, and challenges of integrated care for HIV, non-communicable diseases, and mental health conditions among adolescents and young adults in primary healthcare settings across low- and middle-income countries.
Systematic review conducted according to PRISMA guidelines (PROSPERO: CRD42024567639) across PubMed, Scopus, CINAHL, Web of Science, and Google Scholar.
Included peer-reviewed English studies focusing on integrated care for individuals aged 10–24 years, with study quality appraised using the Mixed Methods Appraisal Tool (MMAT) (N=5 studies: South Africa and Botswana).
Cardiovascular conditions, mental health disorders, obesity, and substance use were the most frequent comorbidities identified alongside HIV.
Integrated care models proved feasible and beneficial for medication adherence and psychosocial support, but implementation was hindered by resource constraints, fragmented delivery, insufficient provider training, and a lack of adolescent-specific guidelines.

Cite This Study

Tsitsi et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec775b70b84ec8b913cfa https://doi.org/10.1186/s12982-026-02724-1

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August 14, 2026Discover Public HealthOpen Access

Integrated management of HIV, non-communicable diseases and mental health in adolescents and young adults in primary health care settings in LMICs: a systematic review

View Full Paper

Ask AI

Bookmark

Authors

ETEdwin Tsitsi TMTshimangadzo Selina Mudau SMSamuel T. Matula

Discussion

Member takes

Overview

Systematic review reveals feasible benefits and systemic barriers for integrated HIV, chronic disease, and mental healthcare in young people, indicating a need for youth-tailored primary care.

Key Points

To evaluate evidence on the implementation, clinical outcomes, and challenges of integrated care for HIV, non-communicable diseases, and mental health conditions among adolescents and young adults in primary healthcare settings across low- and middle-income countries.
Systematic review conducted according to PRISMA guidelines (PROSPERO: CRD42024567639) across PubMed, Scopus, CINAHL, Web of Science, and Google Scholar.
Included peer-reviewed English studies focusing on integrated care for individuals aged 10–24 years, with study quality appraised using the Mixed Methods Appraisal Tool (MMAT) (N=5 studies: South Africa and Botswana).
Cardiovascular conditions, mental health disorders, obesity, and substance use were the most frequent comorbidities identified alongside HIV.
Integrated care models proved feasible and beneficial for medication adherence and psychosocial support, but implementation was hindered by resource constraints, fragmented delivery, insufficient provider training, and a lack of adolescent-specific guidelines.

Cite This Study

Tsitsi et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec775b70b84ec8b913cfa https://doi.org/10.1186/s12982-026-02724-1

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