Clinical perspective demonstrates the value of molecular profiling for salvage surgery in EGFR-mutated lung cancer, suggesting a shift toward biology-guided surgical planning.
work.Salvage surgery after EGFR-TKI therapy should be evaluated not only by whether it can be performed safely, but also by whether it is incorporated into a broader strategy for resistance monitoring and postoperative disease control.In this setting, molecular selection may help shift the evaluation of salvage surgery from anatomical feasibility alone toward biologically informed surgical decision-making.
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Zurui Liu (2026) studied this question.
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