Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 14, 2026AnimalsOpen Access

Modulation of Growth, Intestinal Microbiota, and Immune Responses in Cherax quadricarinatus by Mannan Oligosaccharides

View Full Paper
Ask AI
Bookmark
Share

Authors

KDKe-Xiang DingZZZe‐Long ZhangYLYao-Peng Lu

Discussion

Loading...

Member takes

Overview

Randomized feeding trial demonstrates that dietary mannan oligosaccharides enhance growth, immunity, and gut microbiota in Cherax quadricarinatus, indicating improved disease resistance.

Key Points

  • To evaluate the effects and underlying mechanisms of dietary mannan oligosaccharide supplementation on growth performance, intestinal microbiota, and immune defenses in Cherax quadricarinatus.
  • Randomly assigned Cherax quadricarinatus to six dietary groups containing 0 (M0), 0.2 (M1), 0.4 (M2), 0.6 (M3), 0.8 (M4), or 1.0 (M5) g·kg⁻¹ mannan oligosaccharides for an 8-week feeding trial.
  • Assessed growth metrics, muscle proximate composition, gut microbiota composition, and serum non-specific immune parameters alongside immune-related gene expression.
  • Conducted a pathogenic challenge using Aeromonas hydrophila to evaluate post-infection survival rates across all dietary treatments.
  • The 0.6 g·kg⁻¹ group (M3) achieved significantly higher weight gain rate and specific growth rate compared to control (p < 0.05), alongside reduced muscle lipid content (p < 0.05).
  • Dietary MOS shifted gut microbial profiles by increasing Firmicutes and decreasing Proteobacteria in M3 (p < 0.05), while boosting antioxidant enzymes (SOD, GPx, T-AOC) and upregulating immune genes (GSH-Px, SOD, Trx, LZM, ALF; p < 0.05).
  • Survival rates following Aeromonas hydrophila challenge were significantly higher across all MOS-supplemented groups compared to the non-supplemented control (p < 0.05).

Cite This Study

Ding et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec79cb70b84ec8b914261https://doi.org/10.3390/ani16162511
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dietary black soldier fly oil enhances growth performance, flesh quality, and health status of largemouth bass (Micropterus salmoides)2024 · 15 citations
  2. 2Methodology effects on determining the energy concentration and the apparent total tract digestibility of components in diets fed to growing pigs2018 · 17 citations
  3. 3Haematological modulation and growth of Labeo rohita fingerlings: effect of dietary mannan oligosaccharide, yeast extract, protein hydrolysate and chlorella2009 · 92 citations