Case report demonstrates severe venous thromboembolism as the primary manifestation of minimal change disease in an adult, highlighting critical thrombotic risks in nephrotic syndrome.
This article presents the case of a 52-year-old male who arrived at the emergency department with escalating chest pain and shortness of breath. An urgent CT scan revealed a right pulmonary embolism and inferior vena cava thrombus, prompting immediate anticoagulant therapy. Further diagnostic evaluations confirmed nephrotic syndrome (NS). The patient was discharged on apixaban, ramipril, amlodipine, and atorvastatin. A subsequent renal biopsy showed features consistent with minimal change disease, which resolved spontaneously without the need for steroid treatment. This case highlights the potentially life-threatening presentation of multiple venous thromboses as an initial manifestation of NS.
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Hamed et al. (2024) studied this question.
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