Corticosteroid Therapy of Amyloid Nephrotic Syndrome

Article1 April 1964Corticosteroid Therapy of Amyloid Nephrotic SyndromeMORTON H. MAXWELL, M.D., F.A.C.P., DONALD A. ADAMS, M.D., RALPH GOLDMAN, M.D., F.A.C.P.MORTON H. MAXWELL, M.D., F.A.C.P.Search for more papers by this author, DONALD A. ADAMS, M.D.Search for more papers by this author, RALPH GOLDMAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-4-539 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere is adequate evidence that prolonged corticosteroid therapy is effective in the treatment of the nephrotic syndrome secondary to primary renal disease in both children and adults (1-5). By contrast, there is a striking paucity of published information on the efficacy of steroids in the treatment of the nephrotic syndrome associated with amyloidosis. Furthermore, with more widespread use of percutaneous renal biopsy in the diagnostic workup of nephrotic syndrome of unknown etiology, it has become apparent that amyloidosis is not a rare cause of the nephrotic syndrome in the adult (2, 6-8). In human and in experimental amyloidosis, there is...References1. ADAMSMAXWELLBERNSTEIN DAMHD: Corticosteroid therapy of glomerulonephritis and the nephrotic syndrome: a review: J. Chron. Dis. 15: 29, 1962. CrossrefMedlineGoogle Scholar2. BERMANSCHREINER LBGE: Clinical and histological spectrum of the nephrotic syndrome. Amer. J. Med. 24: 249, 1958. CrossrefMedlineGoogle Scholar3. GOODMANBAXTER HCJH: The nephrotic syndrome. Clinical observations on the therapy with prednisone and other steroids. JAMA 165: 1748, 1957. Google Scholar4. NESSONSPROULRELMANSCHWARTZ HRLEASWB: Adrenal steroids in the treatment of idiopathic nephrotic syndrome in adults. Ann. Intern. Med. 58: 268, 1963. LinkGoogle Scholar5. 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ADAMS, M.D.; RALPH GOLDMAN, M.D., F.A.C.P.Affiliations: Los Angeles, CaliforniaFrom the Departments of Medicine, University of California at Los Angeles Center for the Health Sciences and Wadsworth Veterans Administration Hospital, Los Angeles, California.This work was supported in part by a grant from the University Medical Research Foundation, Los Angeles, California.Requests for reprints should be addressed to Morton H. Maxwell, M.D., 10921 Wilshire Boulevard, Los Angeles, California 90024. 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HOLLEY, M.D.Amyloidosis in childhoodA clinical analysis of the course and prognosis of forty-two patients with amyloidosisAmyloidosis Associated with Rheumatoid ArthritisNiere bei Tumoren, Blutkrankheiten und ParaproteinämienAmyloidosisDeafness, urticaria and amyloidosisSteroid Treatment of the Nephrotic Syndrome in AdultsPrimary amyloidosisSecondary AmyloidosisGlomerulonephritis and other glomerulopathies 1 April 1964Volume 60, Issue 4Page: 539-555KeywordsAmyloidosisCorticosteroid therapyEdemaEtiologyHospital medicineHypertensionHypotensionRenal diseasesSteroidsVeteran care ePublished: 1 December 2008 Issue Published: 1 April 1964 Copyright & PermissionsCopyright ©, 1964, by The American College of PhysiciansPDF downloadLoading ...