Why the study?
Does RT-PCR improve the detection of enterovirus infection compared to conventional virus isolation in hospitalized patients?
Population
113 patients admitted to hospitals in a geographical cluster in Hong Kong in 2010 with laboratory-confirmed…
Comparison
Real-time reverse transcriptase-polymerase chain… vs Conventional virus isolation method
Design
Cohort
Authors
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May improve enterovirus diagnosis via RT-PCR in hospitals; leaves open optimal lab protocols pending prospective data.
Does RT-PCR improve the detection of enterovirus infection compared to conventional virus isolation in hospitalized patients?
RT-PCR significantly improves the laboratory diagnosis and epidemiological delineation of enterovirus infections compared to conventional culture methods.
Lee et al. (2013) studied this question.
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