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June 1, 1988Pain

Postoperative orthopaedic pain — the effect of opiate premedication and local anaesthetic blocks

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Why the study?

Does opiate premedication and/or local anaesthetic block delay the time to first request for postoperative analgesia in patients having orthopaedic surgery?

Population

929 patients having orthopaedic surgery

Comparison

Opiate premedication, local anaesthetic block… vs Neither opiate premedication nor local…

Design

Cohort

Authors

HMH J McQuayDCDawn CarrollRMR Andrew Moore

Discussion

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Overview

Opiate premedication and blocks were associated with delayed analgesia requests after orthopaedic surgery; leaves open effects on total opioid use and recovery.

Structured PICO

Does opiate premedication and/or local anaesthetic block delay the time to first request for postoperative analgesia in patients having orthopaedic surgery?

P
Population
929 patients having orthopaedic surgery
I
Intervention
Opiate premedication, local anaesthetic block, or a combination of both
C
Comparator
Neither opiate premedication nor local anaesthetic block
O
Outcome
Time to first request for postoperative analgesiapatient reported

Opiate premedication and local anaesthetic blocks, especially when combined, significantly prolong the time to first request for postoperative analgesia in orthopaedic surgery patients.

Cite This Study

McQuay et al. (1988) studied this question.

synapsesocial.com/papers/6a7ecec4e9bb045a73c2ff68https://doi.org/10.1016/0304-3959(88)90287-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Failure of interscalene brachial plexus blockade to produce pre-emptive analgesia after shoulder surgery2003 · 7 citations
  2. 2Evaluation of the effect of different block techniques on open-heart surgery in the postoperative period: a prospective observational study2022 · 7 citations
  3. 3A randomized clinical trial comparing six techniques of postoperative analgesia for elective total hip arthroplasty under subarachnoid anesthesia with opioids2021 · 3 citations
  4. 4Timing of Fascial Plane Blocks in Bariatric Surgery: Pre-Incision Administration Is Associated with Lower Early Pain and Opioid Consumption2026
  5. 5Comparison of Analgesia Produced by preoperative Ultrasound-guided Femoral Nerve Blocks and Postoperative Intravenous Administration of Opioids in Patients Undergoing Hip Replacement Surgery2024