Leukemoid Reaction, Hyperuricemia, and Severe Hyperpyrexia Complicating a Fatal Case of Acute Fatty Liver of the Alcoholic

Case Studies1 July 1962Leukemoid Reaction, Hyperuricemia, and Severe Hyperpyrexia Complicating a Fatal Case of Acute Fatty Liver of the AlcoholicROBERT W. COLMAN, M.D., HARVEY M. SHEIN, M.D.ROBERT W. COLMAN, M.D.Search for more papers by this author, HARVEY M. SHEIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-1-110 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlcoholics dying in hepatic failure may be grouped into 3 distinct clinical categories, each correlated with a predominant change in liver histology: portal fibrosis, necrosis, or fatty infiltration (1). The fatal outcome in patients with fibrosis or necrosis may be presumed to be lack of sufficient functioning hepatic tissue. On the other hand, the cause of death is often obscure in those patients whose livers show only fatty infiltration, because it has been shown that fatty change per se does not interfere with most hepatic functions.A case is reported of acute hepatic failure in a young female alcoholic whose...References1. POPPERSZONTO HPB: Fatty liver with hepatic failure in alcoholics. J. Mount Sinai Hosp. 24: 1121, 1957. MedlineGoogle Scholar2. MATEERBALTZMARIONMACMILLAN JGJIDFJM: An improved bromosulfphalein test with a new normal standard. J. A. M. A. 121: 724, 1943. Google Scholar3. BESSEYLOWRYBROCK OAOHMJ: A method for the rapid determination of alkaline phosphatase with 5 cubic millimeters serum. J. Biol. Chem. 164: 321, 1946. CrossrefMedlineGoogle Scholar4. HANGER FM: Serological differentiation of obstruction from hepatogenous jaundice by flocculation of cephalin-cholesterol emulsions. J. Clin. Invest. 18: 261, 1939. CrossrefMedlineGoogle Scholar5. GORNALLBARDAWILLDAVID AACJMM:. 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Author, Article, and Disclosure InformationAffiliations: Boston, MassachusettsFrom the Thorndike Memorial Laboratory and the Second and Fourth (Harvard) Medical Services, Boston City Hospital, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts.Requests for reprints should be addressed to the Director, Second and Fourth (Harvard) Medical Services, Boston City Hospital, Boston, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAlcoholic Liver DiseaseLeukemoid Reaction Associated with Parenteral NutritionSteatosis, cholestasis, and alkaline phosphatase in alcoholic liver diseaseCase 42-1972Intrahepatic Cholestasis vs. Posthepatic Jaundice: Methods of Diagnosis: With a Note on Hypercholesteremic Xanthomatosis in a Patient with Chlorpromazine CholestasisSclerosing Hyaline Necrosis of the Liver in the Chronic Alcoholic A Recognizable Clinical SyndromeHUGH A. EDMONDSON, M.D., F.A.C.P., ROBERT L. PETERS, M.D., TELFER B. REYNOLDS, M.D., F.A.C.P., OLIVER T. KUZMA, M.D. 1 July 1962Volume 57, Issue 1Page: 110-115KeywordsAcute liver failureAlcoholicsFatty liverHospital medicineLiver fibrosisMedical servicesNecrosisPhosphatasesProteinsResearch laboratories Issue Published: 1 July 1962 PDF DownloadLoading ...