Text Messages to Improve Medication Adherence and Secondary Prevention After Acute Coronary Syndrome: The TEXTMEDS Randomized Clinical Trial
Key result
A text message-based program did not significantly improve self-reported medication adherence compared to usual care after acute coronary syndrome (RR 0.93; 95% CI 0.84-1.03; P=0.15).
Why the study?
The study evaluated the effects of text message-delivered cardiac education and support on medication adherence after an acute coronary syndrome.
Does a text message-based education and support program improve self-reported medication adherence in patients after acute coronary syndrome?
Population
1424 patients after acute coronary syndrome from 18 Australian public teaching hospitals
Comparison
Text message-delivered cardiac education and support plus usual care vs usual care alone
Design
Single-blind multicenter randomized controlled trial
Follow-up
12 months
Authors
Discussion
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Member takes
Implication
Do not add text-message programs to usual care for post-ACS adherence; leaves open alternative digital strategies.
Study Design
Type
RCT (n=1,424)
Blinding
Single-blind
Randomization
randomized
Multicenter
Yes
Structured PICO
Does a text message-based education and support program improve self-reported medication adherence in patients after acute coronary syndrome?
P
Population
1,424 patients (mean age 58, 21% female) after acute coronary syndrome, followed for 12 months.
I
Intervention
Multiple motivational and supportive weekly text messages on medications and healthy lifestyle with the opportunity for 2-way communication (text or telephone) added to usual care.
C
Comparator
Usual care (secondary prevention as determined by the treating clinician).
O
Outcome
Self-reported medication adherence (percentage of patients adherent, defined as >80% adherence to each of up to 5 indicated cardioprotective medications, at both 6 and 12 months).patient reported
Main Result
Relative Risk: 0.93 (95% CI 0.84–1.03)
p-value: p=0.15
A text message-based support program did not significantly improve medication adherence after acute coronary syndrome, though it had small positive effects on some lifestyle risk factors.
Cite This Study
Chow et al. (2022) conducted an RCT in Acute coronary syndrome (n=1,424). Text message-delivered cardiac education and support vs. Usual care was evaluated on Self-reported medication adherence (>80% adherence to each of up to 5 indicated cardioprotective medications, at both 6 and 12 months) (RR 0.93, 95% CI 0.84-1.03, p=0.15). A text message-based program did not significantly improve self-reported medication adherence compared to usual care after acute coronary syndrome (RR 0.93; 95% CI 0.84-1.03; P=0.15).