Why the study?
Does baroreflex sensitivity differ between patients with carotid sinus syndrome, sick sinus syndrome, and healthy controls?
Population
11 patients with carotid sinus syndrome, 6 patients with sick sinus syndrome, and 9 age and blood pressure…
Comparison
Phenylephrine pressor test vs Age and blood pressure matched controls, and…
Design
Case-control
Authors
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Heightened baroreflex sensitivity may distinguish carotid sinus from sick sinus syndrome; hypothesis-generating and requires prospective validation.
Does baroreflex sensitivity differ between patients with carotid sinus syndrome, sick sinus syndrome, and healthy controls?
Patients with carotid sinus syndrome manifesting as sinus arrest have an abnormally increased baroreflex sensitivity, suggesting a different pathophysiological mechanism for bradycardia compared to sick sinus syndrome.
Morley et al. (1984) studied this question.
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