Key result
Primary percutaneous coronary intervention for acute STEMI achieved TIMI III flow in 80% of patients and was associated with an in-hospital mortality rate of 3.5%.
Why the study?
Primary PCI is the emergency gold standard for STEMI, and the authors aimed to share the experience and outcomes of primary PCI in a tertiary care hospital in South Punjab, Pakistan.
Cross-Sectional (n=1,132)
No
Primary PCI for STEMI in a developing world tertiary center demonstrates favorable procedural success and low in-hospital mortality despite significant delays in patient presentation.
Acceptable primary PCI outcomes in a developing-world center; leaves open generalizability and causal effects pending prospective trials.
BACKGROUND: Primary percutaneous coronary intervention (PCI) is the emergency procedure and gold standard for the treatment of ST-Elevation Myocardial Infarction (STEMI). OBJECTIVE: To share the experience and outcomes of primary PCI in a tertiary care hospital in South Punjab, Pakistan. METHODS: of September, 2023. All patients presenting with acute STEMI undergoing primary PCI were included in the study. Data regarding patient demographics, risk factors, procedural characteristics, time variables, and in-hospital events was observed. RESULTS: A total of 1132 patients were included in the study. There were 934 (82.5%) males. Smoking is the most common risk factor among all the patients. Anterior wall myocardial infarction is the most common STEMI and the left anterior descending artery is the culprit vessel in 58.3% (n=660) of patients. Single vessel disease was present in 34.6% (n=392) of the patients. Thrombolysis in Myocardial Infarction (TIMI )Flow III was achieved in 80% (n=906) of patients after primary PCI. The average total ischemic time of the patients included in the study was 5 hours and 48 minutes, with a standard deviation of 3 hours and 55 minutes. Our mortality was 3.5% (n=40). CONCLUSION: Our patients take a longer time to present to the PCI-capable centers. Despite their late presentation, primary PCI has better outcomes for treating acute STEMI.
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Akhtar et al. (2023) conducted a cross-sectional in Acute ST-Elevation Myocardial Infarction (STEMI) (n=1,132). Primary Percutaneous Coronary Intervention (PCI) was evaluated on Achievement of TIMI Flow III. Primary percutaneous coronary intervention for acute STEMI achieved TIMI III flow in 80% of patients and was associated with an in-hospital mortality rate of 3.5%.
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