The relationship between maternal psychiatric disorder, autism spectrum disorder and intellectual disability in the child: a composite picture

Objective: Our four previous research papers examined the relationship between maternal psychiatric disorders and having a child with autism spectrum disorder or intellectual disability (ASD or ID). Here, we aimed to discuss and integrate these results. Methods: We used regression analyses of rates based on data from state-based, linkable registries. Results: Women with a psychiatric disorder were about twice as likely to have a child with ASD or ID. Of mothers with no psychiatric history, those with a child with ASD or ID were about twice as likely to have a psychiatric disorder after the birth as mothers with no child with ASD or ID. During the study period, mothers with both a psychiatric disorder and a child with ASD or ID were at the highest risk of death, followed in succession by mothers with only a psychiatric disorder, mothers with only a child with ASD or ID, and mothers with neither a psychiatric disorder nor a child with ASD or ID.