Amyloidosis Complicating Tuberculosis—diagnosis, Prognosis and Treatment

Article1 December 1943AMYLOIDOSIS COMPLICATING TUBERCULOSIS—DIAGNOSIS, PROGNOSIS AND TREATMENTSAMUEL COHEN, M.D., F.A.C.P.SAMUEL COHEN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-6-990 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptI. INTRODUCTIONThe substance, amyloid, is now considered to be a complex protein, the exact chemical composition of which has not yet been definitely determined. The disease, secondary amyloidosis, is looked upon by most contemporary observers as a disturbance of protein metabolism.More effective treatment of syphilis and a more prompt surgical attack on suppurative foci have undoubtedly reduced these two common conditions as potential sources of amyloidosis and have served to center attention on tuberculosis as the chief current cause of this complication. The lesson is obvious. Early and adequate control of precavitary tuberculosis will prevent amyloidosis. The earlier...Bibliography1. BENNHOLD H: Ueber die Ausscheidung intravenös einverleibten Kongorotes bei den verschiedensten Erkrankungen insbesondere bei Amyloidosis, Deutsch. Arch. f. klin. Med., 1923, cxliii, 32-46. Google Scholar2. GERBERFRYCZYNSKI IEM: Use of heparinized blood in studies with congo red and bromsulphalein, Am. Jr. Clin. Path., 1942, xii, 312. CrossrefGoogle Scholar3. FRIEDMANAUERBACH MO: An improved congo red test for amyloidosis, Jr. Lab. and Clin. Med., 1935, xxi, 93. Google Scholar4. PEARLMAN AW: Amyloidosis; clinical and pathological study of 135 cases, Quart. Bull. Sea View Hosp., 1941, vi, 295. Google Scholar5. KUCZYNSKI MH: Edwin Goldmann's Untersuchungen über celluläre Vorgänge im Grund nachgelassener Präparate dargestellt und durch neue Versuche ergänzt, Virchow's Arch. f. path. Anat., 1922, ccxxxix, 185. CrossrefGoogle Scholar6. MORGENSTERN Z: Zur Frage über Amyloidose und Resorption, Virchow's Arch. f. path. Anat., 1926, cclix, 698. CrossrefGoogle Scholar7. GRAYZEL HG: Amyloidosis—experimental studies, Arch. Path., 1934, xvii, 50. Google Scholar8. JAFFÉ RH: Amyloidosis produced by injections of proteins, Arch. Path., 1926, i, 25. Google Scholar9. LETTERER E: Studien über Art und Entstehung des Amyloids, Beitr. z. path. Anat. u. z. allg. Path., 1926, lxxv, 486. Google Scholar10. GAIRDNER WT: Discussion following Delafield's article on Diseases of the Kidneys, Trans. Assoc. Am. Phys., 1891, vi, 149. Google Scholar11. WALKER GF: A case of recovery from amyloid disease, Lancet, 1928, ii, 120. CrossrefGoogle Scholar12. REIMANN HA: Recovery from amyloidosis, Jr. Am. Med. Assoc., 1935, cciv, 1070. CrossrefGoogle Scholar13. MÉTRAUX P: Über Rückbildungsvorgänge bei menschlicher Amyloidose, Frankf. Ztschr. f. Path., 1929, xxxvii, 279. Google Scholar14. HABEIN HC: Amyloidosis; report of a case in which the patient recovered, Proc. Staff Meet. Mayo Clin., 1934, ix, 261. Google Scholar15. ROSENBLATT MB: Recovery from generalized amyloidosis secondary to pulmonary tuberculosis. Report of a case, Arch. Int. Med., 1936, lvii, 562. CrossrefGoogle Scholar16. PEARLMAN AW: Regression of amyloidosis, Quart. Bull. Sea View Hosp., 1940, vi, 92. Google Scholar17. WALDENSTRÖM H: Quoted by MOSCHCOWITZ, E.: The clinical aspects of amyloidosis, ANN. INT. MED., 1936, x, 73. Google Scholar18. SNAPPERCH'IN IKY: Massive amyloidosis of both adrenal cortices; clinical syndrome with pathological findings, Chinese Med. Jr., 1940, lvii, 201. Google Scholar19. WHITBECK BH: Liver meal in the treatment of amyloidosis in surgical tuberculosis, Jr. Bone and Joint Surg., 1932, xiv, 85. Google Scholar20. SYDENSTRICKER VP: Clinical manifestations of nicotinic acid and riboflavin deficiency (pellagra), ANN. INT. MED., 1941, xiv, 1499. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, New York*Received for publication July 22, 1942.From the Hudson County Tuberculosis Hospital, Dr. B. S. Pollak, Medical Director. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Sterilisation, Stability and Toxicity of Congo Red InjectionsThe Resolution of Amyloid SubstancePattern of renal amyloidosis in Indian patients.Amyloidosis Associated with Rheumatoid ArthritisAmyloidosisCardiovascular syphilis with amyloidosis and periods of alternating heart block.AmyloidosisGORDON W. BRIGGSLaryngeal Nodes and the so-called Amyloid Tumour of the Cords 1 December 1943Volume 19, Issue 6Page: 990-1002KeywordsAmyloid proteinsAmyloidosisPathologistsProtein metabolismResearch laboratoriesSyphilis Issue Published: 1 December 1943 PDF downloadLoading ...