Key result
Off-pump coronary artery bypass graft was associated with a significantly longer intensive care unit length of stay compared to on-pump CABG, but showed no significant difference in mortality (OR 1.165).
Why the study?
CABG techniques were compared to identify the most effective method to reduce the cost of prolonged ICU length of stay and mortality.
Does off-pump coronary artery bypass graft reduce intensive care unit length of stay and mortality compared to on-pump coronary artery bypass graft in post-CABG patients?
Observational (n=1,569)
No
Does off-pump coronary artery bypass graft reduce intensive care unit length of stay and mortality compared to on-pump coronary artery bypass graft in post-CABG patients?
Contrary to some previous studies, off-pump CABG was associated with a significantly longer intensive care unit length of stay compared to on-pump CABG, with no significant difference in mortality.
Should not yet alter surgical technique selection; leaves open the clinical importance of ICU stay differences in off-pump CABG.
Background Coronary artery bypass graft ( CABG) techniques, both on-pump (ONCABG) and off-pump (OPCABG), were compared recently in order to seek the most effective technique to reduce the cost of prolonged intensive care unit length of stay (ICU LOS) and mortality. This study aim to compare ICU LOS and mortality in ONCABG and OPCABG Methods Secondary data was used in this study. Statistical analyses were performed in SAS 9.4 (SAS Institute Inc, Cary, NC). The analyses included descriptive statistics for all variables, generalized linear models for ICU LOS, and logistic regression for mortality. All models were fitted in bivariate and multivariate forms to consider multiple factors (i.e., age, sex, race, EF, comorbidities such as hypertension, diabetes, and obesity). Statistical significance was determined at the level of alpha = 0.05. Results Demographic data of 1569 patients shows variance of characteristics. The analysis shows significant and longer ICU LOS in OPCABG (Mean = 0.558; SE = 0.026 vs Mean = 0.408; SE = 0.633; p < 0.001). Similar results were demonstrated after adjustment of covariates effects (OPCABG Mean = 0.816; SE = 0.073 vs ONCABG Mean = 0.661; SE = 0.091). Logistic regression shows that there was no significant difference of mortality in OPCABG and ONCABG, both in the unadjusted (OR = 1.165, 95%, CI = 0.485-2.8) and the adjusted model (OR = 1.165, 95% CI = 0.482–2.817). Conclusion ICU LOS was significantly longer in OPCABG patients than in ONCABG patients. There was no significant difference in mortality between the two groups.
No takes yet. Share an insight, caveat, or question.
Ibrahim et al. (2022) conducted an observational in Coronary Artery Disease (n=1,569). Off-pump coronary artery bypass graft (OPCABG) vs. On-pump coronary artery bypass graft (ONCABG) was evaluated on Mortality (OR 1.165, 95% CI 0.482-2.817, p=0.735). Off-pump coronary artery bypass graft was associated with a significantly longer intensive care unit length of stay compared to on-pump CABG, but showed no significant difference in mortality (OR 1.165).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: