March 1, 2011Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery

Short- and Long-Term Outcomes in Octogenarian Patients Undergoing Off-Pump Coronary Artery Bypass Grafting Compared with On-Pump Coronary Artery Bypass Grafting

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Why the study?

Does off-pump coronary artery bypass grafting reduce mortality compared to on-pump coronary artery bypass grafting in octogenarian patients?

Population

937 patients older than 80 years presenting with multivessel coronary artery disease who underwent primary…

Comparison

Off-pump coronary artery bypass grafting (OPCAB) vs On-pump coronary artery bypass grafting (ONCAB)

Design

Cohort

Follow-up

10 years

Authors

ESEric L. SarinInova Fairfax Hospital MKMichael Owen KayattaUniversity of California, Riverside PKPatrick KilgoEmory University

Discussion

Member takes

Implication

May warrant short-term mortality consideration with OPCAB in octogenarians but should not yet change practice; leaves open confirmation of long-term equivalence in RCTs.

Structured PICO

Does off-pump coronary artery bypass grafting reduce mortality compared to on-pump coronary artery bypass grafting in octogenarian patients?

Population

937 patients older than 80 years (octogenarians) presenting with multivessel coronary artery disease who underwent primary coronary artery bypass grafting (CAB). Mean age ~82.6 years, ~54.6% male.

Intervention

Off-pump coronary artery bypass grafting (OPCAB)

Comparator

On-pump coronary artery bypass grafting (ONCAB)

Outcome

In-hospital mortality and 10-year survival (also evaluated differences in death, stroke, myocardial infarction incidence, and their composite major adverse cardiac events)hard clinical

Off-pump CABG in octogenarians may reduce in-hospital mortality compared to on-pump CABG, though long-term survival remains similar.

Cite This Study

Sarin et al. (2011) studied this question.

synapsesocial.com/papers/6a89384ad42f68325a92ce4e https://doi.org/10.1097/imi.0b013e31821692b1

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Implication

May warrant short-term mortality consideration with OPCAB in octogenarians but should not yet change practice; leaves open confirmation of long-term equivalence in RCTs.

Short- and Long-Term Outcomes in Octogenarian Patients Undergoing Off-Pump Coronary Artery Bypass Grafting Compared with On-Pump Coronary Artery Bypass Grafting

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Short- and Long-Term Outcomes in Octogenarian Patients Undergoing Off-Pump Coronary Artery Bypass Grafting Compared with On-Pump Coronary Artery Bypass Grafting

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider