Key result
Radiofrequency ablation with contact forces of at least 20 grams was required to achieve transmural lesions in a swine model, with force correlating positively with lesion depth (r=0.85, P<0.05).
Why the study?
Does catheter-tissue contact force impact lesion depth and transmurality during cavo-tricuspid isthmus ablation in a swine model?
Population
8 pigs in an experimental electrophysiology laboratory
Comparison
Cavo-tricuspid isthmus radiofrequency ablation… vs Different contact force groups compared to each…
Design
Preclinical
Follow-up
1 week
Authors
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Supports contact force monitoring in ablation models; leaves open human validation for cavo-tricuspid isthmus lesions.
Does catheter-tissue contact force impact lesion depth and transmurality during cavo-tricuspid isthmus ablation in a swine model?
Effect estimate: r = 0.85
p-value: p=< 0.05
In a swine model of cavo-tricuspid isthmus ablation, a contact force of at least 20 g is required to achieve transmural lesions, highlighting the importance of contact force for ablation efficacy.
Francés et al. (2013) studied Cavo-tricuspid isthmus ablation (experimental model) (n=8). Radiofrequency ablation with varying contact forces was evaluated on Lesion depth and transmurality (r = 0.85, p=< 0.05). Radiofrequency ablation with contact forces of at least 20 grams was required to achieve transmural lesions in a swine model, with force correlating positively with lesion depth (r=0.85, P<0.05).
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