Key result
Excessive caffeine intake was not associated with an increased risk of atrial fibrillation compared to minimal intake (OR 1.07; 95% CI 0.63-1.81; P=0.79).
Why the study?
Conflicting findings and high variability exist among published studies regarding the association between caffeine intake and atrial fibrillation risk.
Does excessive caffeine intake increase the risk of atrial fibrillation?
Meta-Analysis (n=1,176,579)
Does excessive caffeine intake increase the risk of atrial fibrillation?
This large meta-analysis demonstrates no significant association between excessive caffeine intake and the risk of atrial fibrillation.
Does not justify routine caffeine restriction to lower AF risk; leaves open standardized prospective studies given high heterogeneity.
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Al-Fadhel et al. (2024) conducted a meta-analysis in Atrial fibrillation (n=1,176,579). Excessive caffeine intake vs. Minimal caffeine intake was evaluated on Risk of atrial fibrillation (OR 1.07, 95% CI 0.63-1.81, p=0.79). Excessive caffeine intake was not associated with an increased risk of atrial fibrillation compared to minimal intake (OR 1.07; 95% CI 0.63-1.81; P=0.79).
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