Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 14, 2004Protein ScienceOpen Access

Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation

View Full Paper
Ask AI
Bookmark
Share

Authors

KAKathleen AertgeertsVertex Pharmaceuticals (United States)SYSheng YeNanjing University of Information Science and TechnologyMTMike TennantImperial College London

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Aertgeerts et al. (2004) studied this question.

synapsesocial.com/papers/6a7f29f7eadf0d493516c1bchttps://doi.org/10.1110/ps.03460604
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1N‐linked glycosylation of dipeptidyl peptidase IV (CD26): Effects on enzyme activity, homodimer formation, and adenosine deaminase binding2003 · 66 citations
  2. 2The CCP4 suite: programs for protein crystallography1994 · 17,396 citations
  3. 3Triggering of the proteinase dipeptidyl peptidase IV (CD26) amplifies human T lymphocyte proliferation1991 · 59 citations
  4. 4Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.1998 · 321 citations
  5. 5G Protein Heterodimers: New Structures Propel New Questions1996 · 206 citations