Key result
Optical coherence tomography (OCT) provides complementary information to traditional angiography for coronary plaque assessment and PCI guidance, though its clinical impact remains modest.
Why the study?
Despite its capabilities, the impact of optical coherence tomography on daily clinical practice remains modest due to a lack of standardized PCI guidance algorithms and prospective clinical trial data.
This narrative review provides a comprehensive overview of OCT interpretation, its applications in PCI guidance, current limitations, and knowledge gaps.
Answers are grounded in this paper and cite their sources.
Offers complementary plaque insights beyond angiography; leaves open whether OCT-guided PCI improves outcomes.
Since its ability to precisely characterized atherosclerotic plaque phenotypes, to tailor stent implantation, as well as to guide both complex percutaneous coronary interventions (PCI) and invasive diagnostic work-ups (e.g., spontaneous coronary dissections or myocardial infarction with non-obstructive arteries), the adoption of optical coherence tomography (OCT) was raised in the past decades in order to provide complementary information to the traditional angiography and to overcome its limitations. However, the impact of OCT on daily clinical practice is currently modest, firstly because of the lack of both standardized algorithms of PCI guidance and data from prospective clinical trials. Therefore, the aim of our narrative review is to provide a comprehensive overview of the basic OCT interpretation, to summarize the evidence supporting the OCT guidance procedures and applications, to discuss its current limitations, and to highlight the knowledge gaps that need to be filled with more robust evidence.
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Viscusi et al. (2023) conducted a review in Coronary Atherosclerotic Plaque. Optical Coherence Tomography (OCT) was evaluated. Optical coherence tomography (OCT) provides complementary information to traditional angiography for coronary plaque assessment and PCI guidance, though its clinical impact remains modest.
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