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May 15, 1991Proceedings of the National Academy of SciencesOpen Access

The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site.

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Authors

TKThomas KjeldsenNovo Nordisk (Denmark)AAAsser S. AndersenStatens Serum InstitutFWFinn C. WibergSymphogen (Denmark)

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Cite This Study

Kjeldsen et al. (1991) studied this question.

synapsesocial.com/papers/6a7f3638b4cedf233c7ca080https://doi.org/10.1073/pnas.88.10.4404
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Also Consider

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  1. 1Identification of a Ligand-Binding Region of the Human Insulin Receptor Encoded by the Second Exon of the Gene1990 · 79 citations
  2. 2The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity. Evidence from receptor chimeras.1990 · 104 citations
  3. 3Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.1982 · 439 citations
  4. 4After Insulin Binds1987 · 679 citations
  5. 5Hormone Binding Site of the Insulin Receptor: Analysis Using Photoaffinity-Mediated Avidin Complexing1989 · 81 citations