Key result
Surgical resection of a norepinephrine-secreting para-aortic paraganglioma resolved heart failure symptoms and improved left ventricular ejection fraction from 35% to 50%.
Why the study?
Phaeochromocytomas/paragangliomas are rare tumours that can cause cardiovascular complications following catecholamine secretion.
Does tumour resection improve heart failure signs and symptoms and LVEF in a patient with catecholamine-induced cardiomyopathy from a paraganglioma?
Case Report (n=1)
No
Does tumour resection improve heart failure signs and symptoms and LVEF in a patient with catecholamine-induced cardiomyopathy from a paraganglioma?
Resection of a norepinephrine-secreting paraganglioma can reverse catecholamine-induced cardiomyopathy and improve left ventricular ejection fraction.
Answers are grounded in this paper and cite their sources.
May warrant paraganglioma evaluation in catecholamine cardiomyopathy; leaves open generalizability from single case.
Phaeochromocytomas/paragangliomas (PPGL) are rare tumours that can cause cardiovascular complications following the secretion of catecholamines. We present a young female presented with heart failure with reduced ejection fraction as a result of norepinephrine secreting para-aortic paraganglioma and improvement of heart failure sign and symptoms and left ventricular ejection fraction following tumour resection.
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Ranjbar et al. (2021) conducted a case report in Catecholamine-induced cardiomyopathy (n=1). Surgical resection of para-aortic paraganglioma was evaluated on Left ventricular ejection fraction (LVEF) and heart failure symptoms. Surgical resection of a norepinephrine-secreting para-aortic paraganglioma resolved heart failure symptoms and improved left ventricular ejection fraction from 35% to 50%.
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