Key result
A baseline time to rise from the floor greater than 7 seconds predicted a more marked decline in 6-minute walk distance over 12 months, particularly in boys older than 7 years.
Why the study?
Does the time to rise from the floor predict changes in the 6-minute walk test over 12 months in ambulant boys with Duchenne Muscular Dystrophy?
Observational (n=215)
Yes
Does the time to rise from the floor predict changes in the 6-minute walk test over 12 months in ambulant boys with Duchenne Muscular Dystrophy?
Absolute Event Rate: -77.84% vs -6.23%
The time to rise from the floor is a significant prognostic factor for predicting 12-month functional decline (measured by 6MWT) in ambulant boys with Duchenne Muscular Dystrophy.
No takes yet. Share an insight, caveat, or question.
Supports floor rise time >7 s for identifying higher-risk DMD boys; extends prognostic data but remains hypothesis-generating.
Mazzone et al. (2016) conducted an observational in Duchenne Muscular Dystrophy (n=215). Time to rise from the floor (TRF) > 7 seconds vs. TRF ≤ 7 seconds was evaluated on 12-month change in 6-minute walk distance (6MWD). A baseline time to rise from the floor greater than 7 seconds predicted a more marked decline in 6-minute walk distance over 12 months, particularly in boys older than 7 years.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: