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November 1, 1979Applied and Environmental MicrobiologyOpen Access

N-demethylation of nicotine and reduction of nicotine-1'-N-oxide by Microsporum gypseum

Robert D. Sindelar John P. N. Rosazza Charles F. Barfknecht

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Abstract

Several microorganisms were examined for their abilities to convert S-nicotine into nornicotine. Five microorganisms including Microsporum gypseum (ATCC 11395) produced nornicotine and three unknown metabolites. M. gypseum efficiently reduced nicotine-1'-N-oxide to nicotine, but no nornicotine was obtained when the N-oxide was used as substrate.

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Sindelar et al. (1979) studied this question.

synapsesocial.com/papers/6a7f49950f8dded440b3d652 https://doi.org/10.1128/aem.38.5.836-839.1979

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