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June 16, 2016Journal of Cardiovascular Electrophysiology

“Cardio‐Neuromodulation” With a Multielectrode Irrigated Catheter: A Potential New Approach for Patients With Cardio‐Inhibitory Syncope

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Why the study?

Does tailored ablation of the anterior right ganglionated plexus prevent syncope in a patient with severe cardio-inhibitory syncope?

Population

16-year-old girl with frequent and prolonged episodes of cardio-inhibitory syncope, n=1.

Design

Case_report

Follow-up

22 months

Authors

PDPhilippe DebruyneElectrophysiology

Discussion

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Implication

May support targeted anterior right ganglionated plexus ablation for refractory cardio-inhibitory syncope; leaves open efficacy and safety in controlled trials.

Structured PICO

Does tailored ablation of the anterior right ganglionated plexus prevent syncope in a patient with severe cardio-inhibitory syncope?

P
Population
16-year-old girl with frequent and prolonged episodes of cardio-inhibitory syncope (>30 times in the 5 years preceding treatment, approximately 10 severe episodes in the previous 12 months), n=1.
I
Intervention
Tailored ablation of the anterior right ganglionated plexus with a multielectrode irrigated catheter (3 minutes of ablation).
O
Outcome
Syncope recurrence and reduction in P-P interval.

Tailored ablation of the anterior right ganglionated plexus may offer a targeted, less extensive neuromodulation approach for treating severe cardio-inhibitory syncope.

Cite This Study

Philippe Debruyne (2016) studied this question.

synapsesocial.com/papers/6a7f67f811d2ce75ff8b1fb5https://doi.org/10.1111/jce.13031

Topics

AF ablation outcomes
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Unifocal Right-Sided Ablation Treatment for Neurally Mediated Syncope and Functional Sinus Node Dysfunction Under Computed Tomographic Guidance2018 · 111 citations
  2. 2Cardioneuroablation for children with syncope2026
  3. 3Syncope or seizure, that is the question: case report of a young patient with convulsive cardioinhibitory syncope treated with cardioneuroablation2024
  4. 4An ultrasimplified technique to perform cardioneuroablation: results from a prospective observational study2026
  5. 5Cardioneuroablation: Catheter Vagal Denervation as a New Therapy for Cardioinhibitory Syncope2020 · 7 citations