Why the study?
Single-center studies suggested strong prognostic value for LGE cardiac magnetic resonance in dilated cardiomyopathy, but multicenter data were needed to evaluate associations with adverse cardiovascular events.
Does the presence of late gadolinium enhancement on cardiac magnetic resonance imaging predict adverse cardiovascular outcomes in patients with dilated cardiomyopathy?
Population
1672 consecutive patients with dilated cardiomyopathy referred for cardiac magnetic resonance at 12 institutions in 4 countries
Comparison
LGE presence vs absence
Design
Multinational retrospective multicenter cohort study
Follow-up
2.3 years (interquartile range, 1.0-4.3)
Authors
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May identify higher-risk DCM patients needing closer follow-up but should not yet change practice; leaves open LGE-guided management trials.
Does the presence of late gadolinium enhancement on cardiac magnetic resonance imaging predict adverse cardiovascular outcomes in patients with dilated cardiomyopathy?
The presence of late gadolinium enhancement on cardiac magnetic resonance imaging is a strong independent predictor of mortality, heart failure progression, and arrhythmic events in patients with dilated cardiomyopathy.
Alba et al. (2020) studied this question.
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