Why the study?
Changes in the neuropeptide Y signaling pathway have been linked to ACS, but the association between variants in the NPY and NPY2R genes and ACS severity required evaluation.
Do variants in the NPY and NPY2R genes associate with the risk and severity of acute coronary syndrome in adults?
Do variants in the NPY and NPY2R genes associate with the risk and severity of acute coronary syndrome in adults?
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Variants in the NPY and NPY2R genes, specifically NPY c.20T>C and NPY2R c.-1116A>G, are associated with the development and early onset of acute coronary syndrome.
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Soares et al. (2021) studied this question.
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