Why the study?
In women with INOCA and persistent angina despite medical therapy, it is unclear whether symptoms stem from worsening or persistent CMD or inadequate therapy.
Does repeat coronary function testing guide medical therapy and improve coronary microvascular dysfunction in women with INOCA and persistent angina?
Does repeat coronary function testing guide medical therapy and improve coronary microvascular dysfunction in women with INOCA and persistent angina?
In women with INOCA and persistent angina, repeat invasive coronary function testing can identify evolving pathophysiological pathways and guide targeted medical therapy, potentially improving coronary flow reserve and patient symptoms.
Women with signs and symptoms of ischemia and no obstructive coronary artery disease (INOCA) often have coronary microvascular dysfunction (CMD). It can be diagnosed by coronary function testing (CFT), which is an invasive coronary angiogram procedure. Frequently, these women have persistent angina despite medical therapy, but it is not clear whether it is due to worsening or persistent CMD or inadequate therapy. In this brief report, we describe findings of repeat CFT in a case series of 12 women undergoing repeat CFT for the assessment of persistent angina in order to better understand the evolving pathology.
No takes yet. Share an insight, caveat, or question.
Suppogu et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: