May 29, 2010Heart
The Global Registry of Acute Coronary Events, 1999 to 2009–GRACE
Structured PICO
P
Population
102,341 patients with acute coronary syndromes (ST-segment elevation myocardial infarction, non-ST-elevation myocardial infarction, or unstable angina)
O
Outcome
In-hospital and post-discharge (6-month) events, patient characteristics, and derivation of predictive risk scores
The GRACE registry established a massive global cohort of over 100,000 ACS patients, providing critical data for understanding patient characteristics, outcomes, and developing widely used predictive risk scores.
Authors
Discussion
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Implication
Establishes feasibility of large-scale international ACS registries with high data quality; leaves open need for contemporary cohorts to validate derived risk tools.
Cite This Study
Fox et al. (2010) studied this question.