February 1, 1992AJP Heart and Circulatory Physiology

Strain distribution in small blood vessels with zero-stress state taken into consideration

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Population

Rat ileal and plantar arterioles, venules, and other small blood vessels with lumen diameters down to…

Comparison

Norepinephrine and EDTA vs Hypothetical vessels having an opening angle of…

Design

Preclinical

Authors

YFY. C. FungVascular Medicine SLS. Q. LiuTsinghua University

Discussion

Member takes

Implication

Accurate microvascular strain calculations require opening-angle correction; extends zero-stress biomechanics in rats but leaves human applicability open.

Structured PICO

Population

Rat ileal and plantar arterioles, venules, and other small blood vessels with lumen diameters down to approximately 50 microns

Intervention

Norepinephrine and EDTA

Comparator

Hypothetical vessels having an opening angle of zero

Outcome

Opening angle (alpha) and strain distribution at zero-stress statesurrogate

Demonstrates that small blood vessels have a significant opening angle at zero-stress state, which is critical for accurate biomechanical strain evaluation.

Cite This Study

Fung et al. (1992) studied this question.

synapsesocial.com/papers/6a7f7d66319b4d83ce65737a https://doi.org/10.1152/ajpheart.1992.262.2.h544

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Implication

Accurate microvascular strain calculations require opening-angle correction; extends zero-stress biomechanics in rats but leaves human applicability open.